Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21825342 | 1.00 | ALDH1A1 (0.38) | ALDH1A1HSD11B1MEN1KMT2A | |
| SCHEMBL14881906 | 1.00 | ALDH1A1 (0.38) | ALDH1A1HSD11B1MEN1KMT2A | |
| SCHEMBL1717495 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1320019 | 0.79 | CARM1 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15422090 | 0.79 | HPGD (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12612018 | 0.79 | HPGD (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28665811 | 0.75 | — | — | |
| SCHEMBL1320532 | 0.75 | KMT2A (0.51) | KMT2A | |
| SCHEMBL15758762 | 0.75 | KMT2A (0.51) | KMT2A | |
| SCHEMBL376615 | 0.75 | KMT2A (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010539-B2 | Pyrazole, triazole and tetrazole orexin receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2018-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010539-B2 | Pyrazole, triazole and tetrazole orexin receptor antagonists | HCRTR2, HCRTR1, NPY5R | ALDH1A1 2378/4885HSD11B1 606/4885MEN1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.