Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556810 | 1.00 | HTT (0.39) | HTTPTGES2LMNACYP19A1MMP3 | |
| Butyric Acid SCHEMBL27770134 | 0.89 | FFAR3 (0.41) | HTTPTGES2CYP19A1ALDH1A1 | |
| SCHEMBL24759247 | 0.87 | HTT (0.41) | HTTPTGES2LMNACYP19A1MMP3 | |
| SCHEMBL14565716 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 | |
| SCHEMBL4753036 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 | |
| SCHEMBL12449331 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 | |
| SCHEMBL14742566 | 0.83 | PRKCD (0.35) | LMNACYP19A1MMP3KDM6BKDM5C | |
| SCHEMBL3397280 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 | |
| SCHEMBL79842 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 | |
| SCHEMBL14580755 | 0.83 | CYP19A1 (0.56) | HTTLMNACYP19A1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018114056-A1 | MICROCAPSULES | SYMRISE AG (DE) | 2018-06-28 | — | — | WO | disclosed |