Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25559590 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL3397280 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL25560369 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL4753036 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL79842 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL29018706 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL14580755 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL14565716 | 1.00 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL8045220 | 0.99 | CYP19A1 (0.55) | CYP19A1EPHX1ALDH1A1NPSR1TSHR | |
| SCHEMBL29748715 | 0.95 | CYP19A1 (0.52) | CYP19A1EPHX1ALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9320705-B2 | Sensation modifying topical composition foam | FOAMIX PHARMACEUTICALS LTD. (IL) | 2016-04-26 | — | — | US | disclosed |
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | FOAMIX LTD. (IL) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | TRPA1, GPR35, TRPV1 | CYP19A1 525/4885EPHX1 1201/4885ALDH1A1 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.