Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.33 |
| ▸ | WNT3A | P56704 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374852 | 0.86 | KDM4E (0.40) | HRH4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL20321283 | 0.68 | HRH4 (0.31) | HRH4 | |
| SCHEMBL20321287 | 0.67 | HRH4 (0.33) | HRH4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21672686 | 0.67 | — | — | |
| SCHEMBL1423043 | 0.61 | ALDH1A1 (0.65) | HRH4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1004852 | 0.61 | ALDH1A1 (0.59) | HRH4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8168410 | 0.59 | ALDH1A1 (0.62) | HRH4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8163967 | 0.59 | ALDH1A1 (0.62) | HRH4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL14128945 | 0.59 | — | — | |
| SCHEMBL30617774 | 0.58 | ALDH1A1 (0.51) | HRH4KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306166-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Aquinnah Pharmaceuticals Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2018119395-A1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |