Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912417 | 0.86 | MCL1 (0.76) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL1269571 | 0.86 | MCL1 (0.56) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11219366 | 0.85 | MCL1 (0.55) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11219368 | 0.85 | MCL1 (0.55) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL13265911 | 0.84 | ATM (0.59) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11978593 | 0.82 | AR (0.54) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL13744660 | 0.82 | GAA (0.56) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11948007 | 0.81 | MAPT (0.58) | MCL1RAB9ANPC1MEN1PKM | |
| SCHEMBL24272665 | 0.79 | MCL1 (0.53) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL10981742 | 0.78 | MCL1 (0.51) | MCL1RAB9ANPC1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018113624-A1 | FUSED IMIDAZOLE COMPOUND HAVING INDOLEAMINE 2,3-DIOXYGENASE INHIBITORY ACTIVITY | 深圳微芯生物科技有限责任公司 | 2018-06-28 | — | — | WO | disclosed |