Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20322904 | 0.85 | MCL1 (0.57) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL9912417 | 0.85 | MCL1 (0.76) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL10970442 | 0.84 | MCL1 (0.51) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL10965240 | 0.84 | ATM (0.58) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11219368 | 0.83 | MCL1 (0.55) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11208180 | 0.83 | RAB9A (0.47) | MCL1RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL13744660 | 0.81 | GAA (0.56) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL11978593 | 0.81 | AR (0.54) | MCL1RAB9ANPC1POLBMEN1 | |
| SCHEMBL19433595 | 0.75 | MCL1 (0.64) | MCL1POLBALDH1A1DRD2DRD4 | |
| SCHEMBL4946959 | 0.74 | ATF4 (0.53) | RAB9ANPC1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |