Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304028 | 1.00 | SCN4A (0.50) | SCN4AMAOALMNASCN1ASCN5A | |
| SCHEMBL28304979 | 1.00 | SCN4A (0.50) | SCN4AMAOALMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL21518136 | 0.98 | LMNA (0.51) | SCN4AMAOALMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL21518135 | 0.98 | LMNA (0.51) | SCN4AMAOALMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL21518168 | 0.98 | LMNA (0.51) | SCN4AMAOALMNASCN1ASCN5A | |
| SCHEMBL8750527 | 0.85 | TACR1 (0.42) | SCN4AMAOALMNASCN1ASCN5A | |
| SCHEMBL4981770 | 0.82 | TACR1 (0.59) | SCN4ACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10913016 | 0.81 | LMNA (0.44) | LMNACYP1A2TSHRSLC6A4TACR1 | |
| SCHEMBL13899599 | 0.80 | KDM4E (0.40) | SCN4ALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4315585 | 0.80 | TAAR1 (0.50) | LMNATSHRTAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051326-A | Nucleoside phosphate compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| WO-2018113652-A1 | NUCLEOSIDE PHOSPHATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-06-28 | — | — | WO | disclosed |