Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548765 | 0.87 | ADORA3 (0.55) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL26693534 | 0.86 | ADORA3 (0.52) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL20879513 | 0.85 | ADORA3 (0.53) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL22241500 | 0.84 | ADORA3 (0.52) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL9152465 | 0.83 | ADORA3 (0.51) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL9152455 | 0.83 | ADORA3 (0.51) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL15075488 | 0.83 | ADORA3 (0.51) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL9548708 | 0.83 | ADORA3 (0.51) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL9548850 | 0.81 | ADORA3 (0.49) | ADORA3PNPPOLBTK1HPRT1 | |
| SCHEMBL9548837 | 0.81 | ADORA3 (0.49) | ADORA3PNPPOLBTK1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |