Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 13/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22083745 | 0.92 | F2 (0.47) | FUT5POLBSTING1F2 | |
| SCHEMBL25964517 | 0.92 | P2RY1 (0.49) | POLB | |
| SCHEMBL20324706 | 0.92 | STING1 (0.47) | FUT5POLBSTING1F2NT5E | |
| SCHEMBL20324836 | 0.92 | STING1 (0.47) | FUT5POLBSTING1F2NT5E | |
| SCHEMBL23477825 | 0.92 | POLB (0.48) | POLBSTING1F2 | |
| SCHEMBL20324889 | 0.91 | STING1 (0.47) | FUT5STING1 | |
| SCHEMBL29331766 | 0.86 | DTYMK (0.41) | POLB | |
| SCHEMBL22524118 | 0.85 | STING1 (0.48) | FUT5POLBSTING1F2NT5E | |
| SCHEMBL22434567 | 0.84 | POLB (0.51) | POLBSTING1F2 | |
| SCHEMBL20326935 | 0.84 | POLB (0.51) | POLBSTING1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |