Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894678 | 0.89 | POLB (0.59) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL21417495 | 0.89 | POLB (0.59) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL20758514 | 0.89 | POLB (0.59) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL18837841 | 0.89 | POLB (0.59) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL26196385 | 0.88 | ALDH1A1 (0.55) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL19145773 | 0.88 | POLB (0.56) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL23679527 | 0.87 | POLB (0.56) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL21896070 | 0.87 | POLB (0.56) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL16221582 | 0.87 | POLB (0.56) | HPRT1POLBNT5EPNPALDH1A1 | |
| SCHEMBL16221580 | 0.87 | POLB (0.56) | HPRT1POLBNT5EPNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |