Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 13/20 | 0.46 |
| ▸ | FHIT | P49789 | 2/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23476832 | 0.90 | NT5E (0.48) | NT5ESTING1FUT5 | |
| SCHEMBL20324630 | 0.90 | STING1 (0.46) | NT5ESTING1FHIT | |
| SCHEMBL22930761 | 0.88 | NT5E (0.52) | NT5EFHITFUT5 | |
| SCHEMBL20325358 | 0.88 | STING1 (0.49) | NT5ESTING1 | |
| SCHEMBL20326953 | 0.88 | STING1 (0.49) | NT5ESTING1 | |
| SCHEMBL22930629 | 0.87 | NT5E (0.51) | NT5EFHIT | |
| SCHEMBL22930743 | 0.87 | NT5E (0.48) | NT5ESTING1FHITFUT5 | |
| SCHEMBL20326954 | 0.86 | STING1 (0.47) | NT5ESTING1 | |
| SCHEMBL20324534 | 0.86 | STING1 (0.47) | NT5ESTING1 | |
| SCHEMBL23476877 | 0.86 | NT5E (0.52) | NT5ESTING1FHITFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |