Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20324534 | 1.00 | STING1 (0.47) | STING1NT5E | |
| SCHEMBL23476786 | 0.93 | STING1 (0.46) | STING1 | |
| SCHEMBL20326934 | 0.93 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL22352078 | 0.92 | RNASEL (0.52) | NT5E | |
| SCHEMBL20325358 | 0.90 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL23476832 | 0.90 | NT5E (0.48) | STING1NT5E | |
| SCHEMBL20326953 | 0.90 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL20326964 | 0.89 | RNASEL (0.48) | NT5E | |
| SCHEMBL22930743 | 0.88 | NT5E (0.48) | STING1NT5E | |
| SCHEMBL21637003 | 0.88 | NT5E (0.44) | STING1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |