Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20328584 | 0.80 | — | — | |
| SCHEMBL29187827 | 0.78 | TSHR (0.40) | TSHRLMNATHRB | |
| SCHEMBL30432424 | 0.78 | TSHR (0.40) | TSHRLMNATHRB | |
| SCHEMBL27850694 | 0.75 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL5704625 | 0.73 | NR1H2 (0.34) | TSHRLMNATHRB | |
| SCHEMBL20328580 | 0.73 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL8763793 | 0.73 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL6300378 | 0.71 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL6307616 | 0.71 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL6300395 | 0.71 | TSHR (0.32) | TSHRLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179120-A1 | Atropisomers and Methods of Altering Enantiomeric Excess | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179120-A1 | Atropisomers and Methods of Altering Enantiomeric Excess | CYP11B2, CYP21A2, CYP11B1 | TSHR 2049/4885LMNA 2207/4885THRB 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.