Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28688615 | 1.00 | TSHR (0.54) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL28470816 | 0.92 | TSHR (0.50) | TSHRDAONAPRTSRD5A2MEN1 | |
| Benzoyl Formic Acid SCHEMBL28686042 | 0.92 | CES2 (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL3683174 | 0.90 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27545709 | 0.87 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL1784044 | 0.86 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28406157 | 0.86 | DAO (0.47) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL5079308 | 0.86 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL5085505 | 0.86 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL29006846 | 0.84 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-112175119-B | Solid catalyst component for olefin polymerization, process for producing the same, olefin polymerization catalyst, and process for olefin polymerization | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116059421-A | Sterile patient clothes and sterile treatment method | 山东圣一医疗科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-112772005-A | Hot melt coating agent for electronic circuit mounting substrate | 积水富乐株式会社 | 2021-05-07 | — | — | CN | claimed |
| CN-112175119-A | Solid catalyst component for olefin polymerization, process for producing the same, olefin polymerization catalyst, and process for olefin polymerization | 中国石油化工股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-112175117-A | Solid catalyst component for olefin polymerization and preparation method thereof, catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| EP-1913069-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007021987-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116041583-B | Catalyst component and catalyst system for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-1834118-A | Catalyst compsns. for olefin polymerization and catalyst thereof | CHINA PETROCHEMICAL CORP (CN) | 2006-09-20 | — | — | CN | disclosed |
| CN-1745144-A | Polycarbonate molding compositions and articles with improved surface aesthetics | GEN ELECTRIC (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1146402-C | Gel compositions and methods | — | 2004-04-21 | — | — | CN | disclosed |
| CN-1436237-A | Nucleotide sequences involved in increasing or decreasing ovulation rate in mammals | AGRES LTD (NZ) | 2003-08-13 | — | — | CN | disclosed |
| CN-1240346-A | Injectable depot gel composition and method of preparing the composition | ALZA CORP (US) | 2000-01-05 | — | — | CN | disclosed |