Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | FURIN | P09958 | 2/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436625 | 0.87 | CA2 (0.46) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL17902993 | 0.87 | CA2 (0.46) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL20158426 | 0.87 | CA2 (0.46) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL14012279 | 0.87 | CA2 (0.46) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL12283259 | 0.87 | CA2 (0.46) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL20332469 | 0.87 | CA2 (0.45) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL20328120 | 0.86 | CA2 (0.44) | CA2MEN1KMT2ASIRT5BACE1 | |
| SCHEMBL17595995 | 0.84 | MEN1 (0.45) | CA2MEN1KMT2ABACE1HDAC4 | |
| SCHEMBL17595996 | 0.84 | MEN1 (0.45) | CA2MEN1KMT2ABACE1HDAC4 | |
| SCHEMBL17595993 | 0.84 | MEN1 (0.45) | CA2MEN1KMT2ABACE1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018115204-A1 | PEPTIDE LIGANDS FOR BINDING TO MT1-MMP | BICYCLETX LIMITED (GB) | 2018-06-28 | — | — | WO | disclosed |