Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20329733 | 1.00 | NPC1 (0.68) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20317285 | 0.91 | NPC1 (0.61) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20317272 | 0.91 | NPC1 (0.61) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20329616 | 0.91 | KDM4E (0.78) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20329731 | 0.91 | KDM4E (0.78) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20317211 | 0.91 | NPC1 (0.77) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20329669 | 0.90 | MAOA (0.56) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20317336 | 0.90 | MAOA (0.59) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20329624 | 0.90 | MAOA (0.76) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| SCHEMBL20329625 | 0.90 | MAOA (0.76) | NPC1RAB9AMAOAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179174-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | THESAN PHARMACEUTICALS, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179174-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | AHR, NR1H2, NR1H3 | NPC1 347/4885RAB9A 3885/4885MAOA 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.