SCHEMBL20331444 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	FGFR1	P11362	12/20	0.38

▸	FGFR4	P22455	17/20	0.37

▸	FGFR2	P21802	4/20	0.36

▸	FGFR3	P22607	4/20	0.36

▸	KMT2A	Q03164	2/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	NPC1	O15118	1/20	0.34

▸	RAB9A	P51151	1/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	CSF1R	P07333	1/20	0.34

▸	CYP3A4	P08684	1/20	0.34

▸	CYP2D6	P10635	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	RPS6KB2	Q9UBS0	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21252036	0.87	FGFR1 (0.38)	FGFR1FGFR4FGFR2FGFR3KMT2A
SCHEMBL21756545	0.77	FGFR4 (0.38)	FGFR1FGFR4FGFR2FGFR3KMT2A
SCHEMBL21252062	0.77	FGFR4 (0.32)	FGFR1FGFR4
SCHEMBL21756586	0.75	FGFR4 (0.38)	FGFR1FGFR4FGFR2FGFR3CYP1A2
SCHEMBL21756604	0.73	FGFR4 (0.37)	FGFR1FGFR4FGFR2FGFR3KMT2A
SCHEMBL21386670	0.73	FGFR4 (0.47)	FGFR1FGFR4FGFR2FGFR3CYP1A2
SCHEMBL21252009	0.70	FGFR4 (0.45)	FGFR1FGFR4FGFR2FGFR3CYP1A2
SCHEMBL24488218	0.69	FGFR1 (0.34)	FGFR1FGFR4FGFR2FGFR3
SCHEMBL18131713	0.69	FGFR4 (0.47)	FGFR1FGFR4FGFR2FGFR3CYP1A2
SCHEMBL18131714	0.69	FGFR4 (0.47)	FGFR1FGFR4FGFR2FGFR3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018113584-A1	FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF	上海和誉生物医药科技有限公司	2018-06-28	—	—	WO	disclosed