Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 12/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21252547 | 0.82 | FGFR1 (0.36) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL21252062 | 0.82 | FGFR4 (0.32) | FGFR1FGFR4 | |
| SCHEMBL21252439 | 0.76 | FGFR1 (0.35) | FGFR1FGFR2FGFR4P2RX3P2RX2 | |
| SCHEMBL20331509 | 0.76 | FGFR1 (0.40) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL21251685 | 0.74 | FGFR4 (0.34) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL21251673 | 0.70 | P2RX3 (0.35) | FGFR4P2RX3P2RX2 | |
| SCHEMBL24488280 | 0.70 | FGFR1 (0.33) | FGFR1FGFR2P2RX3P2RX2FGFR3 | |
| SCHEMBL20331444 | 0.69 | FGFR1 (0.38) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL21251696 | 0.69 | FGFR4 (0.33) | FGFR1FGFR4 | |
| SCHEMBL24488195 | 0.66 | POLB (0.35) | FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524603-B1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2022-06-08 | — | — | EP | disclosed |