Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933268 | 0.85 | PDCD1 (0.65) | PDCD1CD274 | |
| SCHEMBL20294247 | 0.85 | PDCD1 (0.65) | PDCD1CD274 | |
| SCHEMBL29593538 | 0.85 | PDCD1 (0.49) | PDCD1CD274 | |
| SCHEMBL20293441 | 0.85 | PDCD1 (0.49) | PDCD1CD274 | |
| SCHEMBL23244398 | 0.83 | PDCD1 (0.53) | PDCD1CD274 | |
| Potassium Ion SCHEMBL29831283 | 0.82 | PDCD1 (0.46) | PDCD1CD274 | |
| SCHEMBL20324281 | 0.82 | PDCD1 (0.52) | PDCD1CD274 | |
| SCHEMBL30661738 | 0.80 | PDCD1 (0.43) | PDCD1CD274 | |
| SCHEMBL27036555 | 0.79 | PDCD1 (0.57) | PDCD1CD274 | |
| SCHEMBL30684114 | 0.79 | PDCD1 (0.49) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179202-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179202-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | PDCD1 157/4885CD274 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.