SCHEMBL29933268

SCHEMBL29933268

CN1CCc2c(nc(C(=O)Nc3cccc(B4OC(C)(C)C(C)(C)O4)c3Cl)n2C)C1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 20/20 0.65
CD274 Q9NZQ7 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20294247 1.00 PDCD1 (0.65) PDCD1CD274
SCHEMBL23244398 0.91 PDCD1 (0.53) PDCD1CD274
SCHEMBL23685522 0.90 PDCD1 (0.63) PDCD1CD274
SCHEMBL20324281 0.90 PDCD1 (0.52) PDCD1CD274
SCHEMBL27036555 0.87 PDCD1 (0.57) PDCD1CD274
SCHEMBL20293441 0.86 PDCD1 (0.49) PDCD1CD274
SCHEMBL29593538 0.86 PDCD1 (0.49) PDCD1CD274
SCHEMBL20314830 0.85 PDCD1 (0.70) PDCD1CD274
SCHEMBL20332989 0.85 PDCD1 (0.47) PDCD1CD274
Potassium Ion SCHEMBL29831283 0.84 PDCD1 (0.46) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232125-A Multi-substituted benzene immunomodulatory compounds, compositions and uses thereof 杭州和正医药有限公司 2022-10-25 CN disclosed
CN-112812113-B Immunomodulatory compounds, compositions and uses thereof 杭州和正医药有限公司 2022-09-20 CN disclosed