Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20333479 | 0.89 | HTT (0.51) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20332801 | 0.89 | KCNA5 (0.48) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20333474 | 0.88 | NAMPT (0.50) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20332814 | 0.88 | KCNA5 (0.48) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20333476 | 0.88 | LMNA (0.58) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20332816 | 0.87 | KCNA5 (0.52) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20332802 | 0.87 | KCNA5 (0.48) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20332803 | 0.86 | KCNA5 (0.50) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20333475 | 0.85 | LMNA (0.48) | SMN1; SMN2KCNA5LMNAHTTKCNA3 | |
| SCHEMBL20333478 | 0.85 | LMNA (0.58) | SMN1; SMN2KCNA5LMNAHTTKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018117166-A1 | THIAZOLE DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT OF SAME | キッセイ薬品工業株式会社 | 2018-06-28 | — | — | WO | disclosed |