Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547192 | 0.68 | — | — | |
| SCHEMBL27447443 | 0.66 | KMT2A (0.43) | TOP1KMT2AMAPTS100A4SMN1; SMN2 | |
| SCHEMBL6228672 | 0.65 | — | — | |
| SCHEMBL27532472 | 0.64 | MAPT (0.46) | TOP1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5475783 | 0.60 | TOP1 (0.50) | TOP1KMT2AMAPTS100A4SMN1; SMN2 | |
| SCHEMBL6089366 | 0.60 | PARP1 (0.35) | — | |
| SCHEMBL31517375 | 0.59 | KMT2A (0.68) | TOP1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL31141901 | 0.59 | — | — | |
| SCHEMBL11694814 | 0.58 | KMT2A (0.55) | TOP1KMT2AMAPTS100A4SMN1; SMN2 | |
| SCHEMBL5551848 | 0.58 | LMNA (0.64) | KMT2AMAPTPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066864-A1 | METHOD AND COMPOSITIONS FOR INHIBITION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-06-09 | — | — | WO | claimed |
| WO-2011066864-A1 | METHOD AND COMPOSITIONS FOR INHIBITION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-06-09 | — | — | WO | disclosed |