Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314854 | 0.89 | TEAD1 (0.34) | TEAD1JAK3 | |
| SCHEMBL23323368 | 0.81 | JAK3 (0.35) | TEAD1JAK3 | |
| SCHEMBL23583943 | 0.76 | TEAD1 (0.34) | TEAD1JAK3 | |
| SCHEMBL20314874 | 0.73 | TEAD1 (0.36) | TEAD1JAK3 | |
| SCHEMBL20314946 | 0.72 | TEAD1 (0.33) | TEAD1JAK3 | |
| SCHEMBL23308415 | 0.71 | JAK3 (0.38) | TEAD1JAK3 | |
| SCHEMBL23569900 | 0.71 | JAK3 (0.38) | TEAD1JAK3 | |
| SCHEMBL20314855 | 0.71 | BTK (0.34) | TEAD1JAK3 | |
| SCHEMBL20314879 | 0.71 | JAK3 (0.38) | TEAD1JAK3 | |
| SCHEMBL20314921 | 0.70 | TEAD1 (0.34) | TEAD1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119183-A2 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. (US) | 2018-06-28 | — | — | WO | disclosed |