Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036500 | 0.94 | TSHR (0.37) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL2031734 | 0.92 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL2035694 | 0.92 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL2031513 | 0.92 | TSHR (0.33) | TSHRTHRBLMNA | |
| SCHEMBL2033055 | 0.86 | TSHR (0.33) | TSHRTHRBLMNA | |
| SCHEMBL2034165 | 0.83 | CYP1A2 (0.33) | TSHRTHRBLMNA | |
| SCHEMBL2034199 | 0.83 | CYP1A2 (0.33) | TSHRTHRBLMNA | |
| SCHEMBL16497428 | 0.82 | — | — | |
| SCHEMBL9285123 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL9281506 | 0.80 | TSHR (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8497391-B2 | Insulating film material, method of film formation using insulating film material, and insulating film | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2013-07-30 | — | — | US | disclosed |
| CN-102906865-A | Low dielectric constant interlayer insulating film and method for forming low dielectric constant interlayer insulating film | TAIYO NIPPON SANSO CORP | 2013-01-30 | — | — | CN | disclosed |
| US-20120328798-A1 | INTER-LOW-PERMITTIVITY LAYER INSULATING FILM, AND METHOD FOR FORMING INTER-LOW-PERMITTIVITY LAYER INSULATING FILM | TRI CHEMICAL LABORATORIES INC. (JP) | 2012-12-27 | — | — | US | disclosed |
| US-20110130584-A1 | INSULATING FILM MATERIAL, METHOD OF FILM FORMATION USING INSULATING FILM MATERIAL, AND INSULATING FILM | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2011-06-02 | — | — | US | disclosed |
| US-5663397-A | MULTISTAGE PROCESS FORMING OXYSILICON RING ENLARGEMENT BY REACTION WITH ACID HALIDE IN THE PRESENCE OF PALLADIUM CATALYST AND ORGANIC BASE | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1997-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130584-A1 | INSULATING FILM MATERIAL, METHOD OF FILM FORMATION USING INSULATING FILM MATERIAL, AND INSULATING FILM | C5, CFH, C9 | TSHR 4538/4885THRB 4670/4885LMNA 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.