Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604333 | 0.77 | SMN1; SMN2 (0.36) | KDRSMN1; SMN2 | |
| SCHEMBL10733772 | 0.77 | GAA (0.47) | KDRNPC1SMN1; SMN2GAA | |
| SCHEMBL20334806 | 0.76 | RET (0.37) | — | |
| SCHEMBL891 | 0.73 | SMN1; SMN2 (0.46) | RIPK2LCKKDRTGFBR1NPC1 | |
| SCHEMBL21625524 | 0.73 | — | — | |
| SCHEMBL20334949 | 0.72 | — | — | |
| SCHEMBL24467951 | 0.68 | CYP1A2 (0.34) | — | |
| SCHEMBL6196856 | 0.68 | RIPK2 (0.35) | RIPK2LCKKDRTGFBR1SMN1; SMN2 | |
| SCHEMBL24467994 | 0.67 | CCNA2 (0.39) | — | |
| SCHEMBL17076776 | 0.66 | ALDH1A1 (0.41) | RIPK2LCKKDRTGFBR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | RIPK2 1161/4885LCK 3/4885KDR 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.