Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334661 | 0.92 | — | — | |
| SCHEMBL4681944 | 0.84 | SMN1; SMN2 (0.42) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL22764428 | 0.83 | MEN1 (0.35) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL21725691 | 0.83 | MEN1 (0.35) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL22764123 | 0.83 | MEN1 (0.35) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL345668 | 0.82 | SMN1; SMN2 (0.39) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL21725682 | 0.79 | MEN1 (0.32) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL20334870 | 0.78 | MEN1 (0.31) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL17859041 | 0.72 | — | — | |
| SCHEMBL12536121 | 0.70 | NCF1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | MEN1 2963/4885ALDH1A1 4032/4885LMNA 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.