Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.46 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342215 | 1.00 | TASP1 (0.46) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20335561 | 1.00 | TASP1 (0.46) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20335563 | 1.00 | TASP1 (0.46) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL21516441 | 0.94 | TASP1 (0.45) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20335576 | 0.87 | TASP1 (0.47) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20335572 | 0.87 | TASP1 (0.47) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20335574 | 0.87 | TASP1 (0.47) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL21515972 | 0.87 | TASP1 (0.47) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20342204 | 0.87 | TASP1 (0.47) | TASP1MAGI3CASP1CASP3CASP4 | |
| SCHEMBL20342186 | 0.86 | MAGI3 (0.46) | TASP1MAGI3CASP1CASP3CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | claimed |
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |