TASP1

Threonine aspartase 1 · Q9H6P5 · TASP1 on Sugi Atlas →

1,034 patent compounds predicted against TASP1, 654 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL10039101 SCHEMBL10039101 1.00 2/20
SCHEMBL10039102 SCHEMBL10039102 1.00 2/20
SCHEMBL18499095 SCHEMBL18499095 0.63 2/20
SCHEMBL2900024 SCHEMBL2900024 0.52 2/20
SCHEMBL7128280 SCHEMBL7128280 0.46 2/20
SCHEMBL345316 SCHEMBL345316 1.00 1/20
SCHEMBL10068891 SCHEMBL10068891 1.00 1/20
SCHEMBL10069051 SCHEMBL10069051 1.00 1/20
SCHEMBL10069054 SCHEMBL10069054 1.00 1/20
SCHEMBL10069116 SCHEMBL10069116 1.00 1/20
SCHEMBL10069516 SCHEMBL10069516 1.00 1/20
SCHEMBL10069515 SCHEMBL10069515 0.85 1/20
SCHEMBL1898696 SCHEMBL1898696 0.81 1/20
SCHEMBL10069115 SCHEMBL10069115 0.73 1/20
SCHEMBL1899805 SCHEMBL1899805 0.71 1/20
SCHEMBL22999953 SCHEMBL22999953 0.68 1/20
SCHEMBL1898992 SCHEMBL1898992 0.68 1/20
SCHEMBL1900846 SCHEMBL1900846 0.67 1/20
SCHEMBL1899142 SCHEMBL1899142 0.65 1/20
SCHEMBL1903539 SCHEMBL1903539 0.65 1/20

Clinical trials — most relevant to TASP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study) PHASE3COMPLETED
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung PHASE2COMPLETED
Effects of Vitamin B3 in Patients With Ataxia Telangiectasia PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
D-aspartate and Therapeutic Exercise EARLY_PHASE1UNKNOWN
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults nanCOMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer nanUNKNOWN
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia nanUNKNOWN
Whole Body MRI for Cancer Surveillance in A-T nanCOMPLETED
Study of Taste Deficits nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Genome Environment Microbiome and Metabolome in Autism Study nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Marker of Brain Insulin Resistance in AD Prognosis nanNOT_YET_RECRUITING
Susceptibility to Infections in Ataxia Telangiectasia nanCOMPLETED
Aswan Heart Centre - Egyptian Healthy Volunteers nanRECRUITING
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations nanUNKNOWN
MOLECULAR REGULATION OF MUSCLE GLUCOSE METABOLISM (AIMS 2A, 2B, 3) nanUNKNOWN
JAK-STAT Signalling Pathway in Familial Myeloproliferative Disorders nanCOMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TASP1 binder may also engage these)

ProteinNameSimilarity
Q8R1G1 1.000 Q8R1G1 →
Q3ZBL5 0.949 Q3ZBL5 →
Q4R4U1 0.946 Q4R4U1 →
Q9NVE7 0.946 Q9NVE7 →
Q5R5F8 0.946 Q5R5F8 →
Q923S8 0.943 Q923S8 →
A4FUF0 0.941 A4FUF0 →
METTL16 RNA N(6)-adenosine-methyltransferase METTL16 0.941 landscape →
Q5R7T2 0.941 Q5R7T2 →
O15315 0.941 O15315 →
Q5RKH0 0.940 Q5RKH0 →
Q7Z6V5 0.940 Q7Z6V5 →
Q7Z624 0.939 Q7Z624 →
Q922P9 0.939 Q922P9 →
Q9CQG2 0.938 Q9CQG2 →
Q6AXQ0 0.937 Q6AXQ0 →
Q5ZIA0 0.937 Q5ZIA0 →
Q6P6J0 0.937 Q6P6J0 →
Q5ZLS7 0.937 Q5ZLS7 →
Q49A26 0.937 Q49A26 →
Q91YD4 0.936 Q91YD4 →
Q8CIW5 0.936 Q8CIW5 →
Q6DC64 0.936 Q6DC64 →
Q9R1T2 0.936 Q9R1T2 →
Q96RR1 0.935 Q96RR1 →
Q9Y3E5 0.934 Q9Y3E5 →
RO60 RNA-binding protein RO60 0.934 landscape →
Q5RKN4 0.933 Q5RKN4 →
Q6P4H8 0.933 Q6P4H8 →
Q8NHH1 0.932 Q8NHH1 →