Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482305 | 0.80 | PREP (0.44) | PREPCA12CA1CA9 | |
| Methyl Alcohol SCHEMBL4028549 | 0.77 | PREP (0.41) | PREPCA12CA1CA9 | |
| SCHEMBL6763899 | 0.76 | PREP (0.53) | PREPCA12CA1CA9 | |
| SCHEMBL16411531 | 0.73 | RAD52 (0.44) | PREPCA12CA1CA9 | |
| SCHEMBL23491348 | 0.70 | PREP (0.57) | PREPCA12CA1CA9 | |
| SCHEMBL20358470 | 0.70 | PREP (0.49) | PREPCA12CA1CA9 | |
| SCHEMBL614621 | 0.69 | PREP (0.47) | PREPCA12CA1CA9 | |
| SCHEMBL8138379 | 0.69 | PREP (0.51) | PREPCA12CA1CA9 | |
| SCHEMBL3057447 | 0.69 | CA1 (0.50) | PREPCA12CA1CA9 | |
| SCHEMBL28993177 | 0.69 | PREP (0.47) | PREPCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414754-B2 | Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2019-09-17 | — | — | US | disclosed |
| US-20180186771-A1 | INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186771-A1 | INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IDO1, API5, IDO2 | PREP 2399/4885CA12 4697/4885CA1 4471/4885 |
| US-10414754-B2 | Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them | IDO1, API5, IDO2 | PREP 2399/4885CA12 4697/4885CA1 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.