Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL4028549 | 0.96 | PREP (0.41) | PREPCA12CA1CA9KIF11 | |
| SCHEMBL6763899 | 0.85 | PREP (0.53) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL16411531 | 0.83 | RAD52 (0.44) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL20336328 | 0.80 | PREP (0.38) | PREPCA12CA1CA9 | |
| SCHEMBL23491348 | 0.79 | PREP (0.57) | PREPCA12CA1CA9KIF11 | |
| SCHEMBL2368966 | 0.79 | PREP (0.45) | PREPCA12CA1CA9CYP2D6 | |
| SCHEMBL20358470 | 0.79 | PREP (0.49) | PREPCA12CA1CA9NPC1 | |
| SCHEMBL614621 | 0.77 | PREP (0.47) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL3057447 | 0.77 | CA1 (0.50) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL8138379 | 0.77 | PREP (0.51) | PREPCA12CA1CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233769-B1 | Imidazole derivatives | SMITHKLINE BEECHAM PLC (GB) | 2007-12-26 | — | — | EP | disclosed |
| US-7189745-B1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20070010534-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2007-01-11 | — | — | US | disclosed |
| EP-1233769-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2004-12-29 | — | — | EP | disclosed |
| EP-1233769-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001037835-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010534-A1 | NOVEL COMPOUNDS | TIE1, TEK, VEGFA | PREP 3795/4885CA12 2982/4885CA1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.