⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305 | 1.00 | — | — | |
| SCHEMBL169459 | 0.96 | — | — | |
| SCHEMBL11100623 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL5571338 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL20610044 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL307959 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL5574655 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL9023160 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL5273324 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL22186740 | 0.96 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586353-A | A kind of luminous organic material and its preparation method and application based on anthracene and its derivative | 华南理工大学 | 2018-09-28 | — | — | CN | claimed |
| US-4638082-A | Method of producing the p-chlorophenol ester of p-chlorophenoxyisobutyric acid | SOCIETE CORIAL, S.A. (FR) | 1987-01-20 | — | — | US | claimed |
| WO-2024137752-A1 | AZEPINO[4,5-B]INDOLONE CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-116239623-A | Preparation method and application of boric acid ester | 江西亚太科技发展有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023031972-A1 | NOVEL SOLID STATE EMITTERS BASED ON PYRIDINIUM SCAFFOLDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-03-09 | — | — | WO | disclosed |
| EP-3915557-A1 | METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS | Aurigene Discovery Technologies Limited (IN) | 2021-12-01 | — | — | EP | disclosed |
| US-11147801-B2 | Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2021-10-19 | — | — | US | disclosed |
| EP-3615027-B1 | METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-07-14 | — | — | EP | disclosed |
| CN-112789035-A | Benzocycloheptene analogs and related compounds having activity as anticancer agents | 贝勒大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-110997654-A | Indole derivatives and uses thereof | 诺华股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| US-20200078339-A1 | METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2020-03-12 | — | — | US | disclosed |
| US-20070060584-A1 | Biaryl substituted thiazoles, oxazoles and imidazoles as sodium channel blockers | MERCK & CO., INC. | 2007-03-15 | — | — | US | disclosed |
| US-20060183785-A1 | Biaryl substituted pyrazoles as sodium channel blockers | MERCK SHARP & DOHME CORP. | 2006-08-17 | — | — | US | disclosed |
| EP-1622911-A2 | PYRROLO[1,2-B]PYRIDAZINE COMPOUNDS AND THEIR USE AS CRF-1 RECEPTOR ANTAGONISTS | Pharmacia & Upjohn Company LLC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1618099-A2 | BIARYL SUBSTITUTED THIAZOLES, OXAZOLES AND IMIDAZOLES AS SODIUM CHANNEL BLOCKERS | Merck & Co., Inc. (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1615895-A1 | BIARYL SUBSTITUTED PYRAZOLES AS SODIUM CHANNEL BLOCKERS | Merck & Co., Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040242587-A1 | Pyrrolo[1,2-b]pyridazine compounds | PFIZER INC | 2004-12-02 | — | — | US | disclosed |
| WO-2004099213-A2 | PYRROLO (1,2-B) PYRIDAZINE COMPOUNDS AND THEIR USE AS CRF-1 RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004094395-A2 | BIARYL SUBSTITUTED THIAZOLES, OXAZOLES AND IMIDAZOLES AS SODIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2004092140-A1 | BIARYL SUBSTITUTED PYRAZOLES AS SODIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2004-10-28 | — | — | WO | disclosed |