SCHEMBL2033972

SCHEMBL2033972

[c]1ccc2c(c1)CSS2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636838 0.83
SCHEMBL4928628 0.65
SCHEMBL240717 0.65
SCHEMBL12472958 0.64
SCHEMBL5827841 0.63 KDM4E (0.32)
SCHEMBL128856 0.63 HPGD (0.33)
SCHEMBL6553886 0.63
SCHEMBL2747368 0.61 ALDH1A1 (0.46)
SCHEMBL3633989 0.61
SCHEMBL5827677 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680118-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2014-03-25 US disclosed
US-20130012541-A1 Therapeutic Agents Useful for Treating Pain PURDUE PHARMA L.P. (US) 2013-01-10 US disclosed
US-8227467-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2012-07-24 US disclosed
US-20110152324-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN PURDUE PHARMA L.P. (US) 2011-06-23 US disclosed
US-7683063-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2010-03-23 US disclosed
EP-2060260-A1 Therapeutic agents useful for treating pain Euro-Celtique S.A. (LU) 2009-05-20 EP disclosed
EP-1862458-B1 Therapeutic agents useful for treating pain EURO CELTIQUE SA (LU) 2008-11-05 EP disclosed
EP-1862458-A2 Therapeutic agents useful for treating pain EURO-CELTIQUE S.A. (LU) 2007-12-05 EP disclosed
EP-1631285-B1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN EURO CELTIQUE SA (LU) 2007-08-08 EP disclosed
US-20070027159-A1 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. 2007-02-01 US disclosed
EP-1631285-A4 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN EURO CELTIQUE SA (LU) 2006-11-02 EP disclosed
EP-1631285-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN Euro-Celtique, S.A. (LU) 2006-03-08 EP disclosed
WO-2005004866-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN EURO-CELTIQUE, S.A. (LU) 2005-01-20 WO disclosed