Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 15/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20338177 | 0.83 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL20338278 | 0.82 | CYP11B2 (1.00) | CYP11B2CYP11B1ADRB1ADRA2ACYP19A1 | |
| SCHEMBL20340221 | 0.81 | CYP11B2 (0.74) | CYP11B2CYP11B1 | |
| SCHEMBL20340087 | 0.80 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL20340137 | 0.80 | CYP11B2 (0.73) | CYP11B2CYP11B1 | |
| SCHEMBL20340102 | 0.80 | CYP11B2 (0.70) | CYP11B2CYP11B1 | |
| SCHEMBL20340231 | 0.80 | CYP11B2 (0.70) | CYP11B2CYP11B1 | |
| SCHEMBL20340152 | 0.79 | CYP11B2 (0.70) | CYP11B2CYP11B1 | |
| SCHEMBL20339921 | 0.79 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL20340229 | 0.78 | CYP11B2 (0.71) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562487-A2 | METALLOENZYME INHIBITOR COMPOUNDS | Selenity Therapeutics (Bermuda), Ltd. (BM) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018125800-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS (BERMUDA), LTD. (BM) | 2018-07-05 | — | — | WO | disclosed |