SCHEMBL20340906

SCHEMBL20340906

CC(N)CC(=O)c1ccccc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.47
HSD17B10 Q99714 8/20 0.47
CFTR P13569 1/20 0.47
KDM4E B2RXH2 9/20 0.46
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
HIF1A Q16665 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FADS1 O60427 1/20 0.41
HPGD P15428 5/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 3/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483631 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL1260279 0.87 ALDH1A1 (0.49) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL27373844 0.82 ALDH1A1 (0.45) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL7809894 0.82 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL17718268 0.82 KDM4E (0.46) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL17483038 0.82 KDM4E (0.46) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL17718270 0.82 KDM4E (0.46) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL11502821 0.82 ALDH1A1 (0.45) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL20340867 0.82 ALDH1A1 (0.49) ALDH1A1HSD17B10CFTRKDM4EMAPT
SCHEMBL26085826 0.81 ALDH1A1 (0.47) ALDH1A1HSD17B10CFTRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190707-A1 COMPOSITION FOR PREVENTING OR TREATING SENSORINEURAL HEARING LOSS 国立大学法人大阪大学 2023-10-05 WO disclosed
WO-2023190707-A1 COMPOSITION FOR PREVENTING OR TREATING SENSORINEURAL HEARING LOSS 国立大学法人大阪大学 2023-10-05 WO disclosed
US-10683335-B2 Freeze-dried preparation containing high-purity PTH and method for producing same ASAHI KASEI PHARMA CORPORATION (JP) 2020-06-16 US disclosed
EP-3079015-B1 PHOTOMASK BLANK, RESIST PATTERN FORMING PROCESS, AND METHOD FOR MAKING PHOTOMASK SHINETSU CHEMICAL CO (JP) 2020-04-29 EP disclosed
US-10011643-B2 Freeze-dried preparation containing high-purity PTH and method for producing same ASAHI KASEI PHARMA CORPORATION (JP) 2018-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011643-B2 Freeze-dried preparation containing high-purity PTH and method for producing same PTH1R, PTMS, VIP ALDH1A1 4716/4885HSD17B10 3505/4885CFTR 2003/4885
US-10683335-B2 Freeze-dried preparation containing high-purity PTH and method for producing same PTH1R, PTMS, VIP ALDH1A1 4700/4885HSD17B10 2623/4885CFTR 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.