Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578645 | 0.87 | FOLH1 (0.51) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL29488080 | 0.87 | FOLH1 (0.51) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL10421300 | 0.86 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL10422860 | 0.86 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL10422861 | 0.86 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL11286662 | 0.84 | NOD1 (0.65) | NOD1SLC6A5 | |
| SCHEMBL9810228 | 0.84 | NOD1 (0.65) | NOD1SLC6A5 | |
| SCHEMBL11279416 | 0.84 | NOD1 (0.65) | NOD1SLC6A5 | |
| SCHEMBL9810230 | 0.84 | NOD1 (0.65) | NOD1SLC6A5 | |
| SCHEMBL29777788 | 0.82 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLAGNPATNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032286-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-02-04 | — | — | US | disclosed |
| US-20210024574-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10894807-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200377549-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2020-12-03 | — | — | US | disclosed |
| US-10011632-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2018-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894807-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NAALAD2 31/4885RIMKLA 360/4885 |
| US-20200377549-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NAALAD2 31/4885RIMKLA 360/4885 |
| US-20210032286-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NAALAD2 31/4885RIMKLA 360/4885 |
| US-10011632-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NAALAD2 31/4885RIMKLA 360/4885 |
| US-20210024574-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NAALAD2 31/4885RIMKLA 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.