Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.32 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341808 | 0.93 | CTSL (0.47) | CTSLTACR2CTSSCTSKCTSB | |
| SCHEMBL20341771 | 0.90 | CTSL (0.38) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18616590 | 0.87 | CTSC (0.41) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL20341762 | 0.84 | CTSL (0.46) | CTSLTACR2CTSSCTSKCTSB | |
| SCHEMBL18615957 | 0.83 | TACR2 (0.37) | CTSLTACR2CTSSCTSKCTSB | |
| SCHEMBL18615884 | 0.83 | CTSL (0.44) | CTSLTACR2CTSSCTSKCTSB | |
| SCHEMBL20335394 | 0.81 | CTSL (0.37) | CTSLTACR2CTSSCTSKANO1 | |
| SCHEMBL23810312 | 0.81 | CTSL (0.49) | CTSLTACR2CTSSCTSKCTSB | |
| SCHEMBL20341828 | 0.80 | CTSL (0.37) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18617379 | 0.80 | NPC1 (0.42) | CTSLTACR2CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |