SCHEMBL20341874

SCHEMBL20341874

C[N+]1(C)CCN(c2nn3c(c2N)CCCC=C3)CC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
CHRNB2 P17787 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14022720 0.92 CYP3A4 (0.32) CYP3A4ALOX15CHRNB2NFKB1MAPK1
SCHEMBL15046469 0.73 CYP3A4 (0.31) CYP3A4ALOX15CHRNB2NFKB1MAPK1
Hydrochloric Acid SCHEMBL16267849 0.71
SCHEMBL15046465 0.70
SCHEMBL15046481 0.64
SCHEMBL14022647 0.62 CHRNB2 (0.34) CHRNB2CHRNA3CHRNA7CHRNA4
SCHEMBL3852468 0.60 CYP3A4 (0.39) CYP3A4ALOX15CHRNB2NFKB1MAPK1
Hydrochloric Acid SCHEMBL15302542 0.59 CYP3A4 (0.41) CYP3A4ALOX15CHRNB2NFKB1MAPK1
SCHEMBL3858146 0.59 CYP3A4 (0.35) CYP3A4ALOX15CHRNB2NFKB1MAPK1
SCHEMBL15046470 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155152-B1 COLOURING COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND EXHIBITING AN ACIDIC PH OREAL (FR) 2018-07-04 EP disclosed