SCHEMBL20344377

SCHEMBL20344377

CCC(C)(C)OC(=O)COc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
ALPL P05186 2/20 0.47
ALPI P09923 2/20 0.47
ALPG P10696 2/20 0.47
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.44
NPC1 O15118 2/20 0.44
LMNA P02545 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 1/20 0.43
PTPN1 P18031 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16272652 0.87 SMN1; SMN2 (0.44) ALOX15MAPTMEN1KMT2AKDM4E
SCHEMBL23850329 0.85 ALOX15 (0.50) ALOX15ALPLALPIALPGMAPT
SCHEMBL2448079 0.84 ALOX15 (0.57) ALOX15ALPLALPIALPGMAPT
SCHEMBL28442553 0.84 ALOX15 (0.49) ALOX15ALPLALPIALPGMAPT
SCHEMBL28937245 0.84 ALOX15 (0.49) ALOX15ALPLALPIALPGMAPT
SCHEMBL16272656 0.83 MAPT (0.41) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL24533746 0.81 ALOX15 (0.46) ALOX15ALPLALPIALPGMAPT
SCHEMBL29271582 0.80 ALOX15 (0.45) ALOX15ALPLALPIALPGMAPT
SCHEMBL20029822 0.79 SMN1; SMN2 (0.50) MAPTMEN1KMT2AKDM4ENPC1
SCHEMBL20029826 0.78 KMT2A (0.46) MAPTMEN1KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355117-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-07-16 CN disclosed
CN-111936487-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-09 CN disclosed
CN-111936136-B Novel imidazopyrimidine compounds and uses thereof 儿童医学中心公司 2024-07-05 CN disclosed
CN-113710660-B DOT1L degradation agent and application thereof 达纳-法伯癌症研究公司 2024-07-02 CN disclosed
CN-112312909-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-02 CN disclosed
CN-114751920-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-114736219-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-118139977-A Double-stranded oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139629-A Compositions and methods for editing MECP2 transcripts 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139851-A Antitumor compounds 法马马有限公司 2024-06-04 CN disclosed
CN-106068325-A CHIRAL DESIGN 波涛生命科学有限公司 2016-11-02 CN disclosed
CN-105960265-A Method for treating wound healing using chemically modified oligonucleotides 阿克赛医药公司 2016-09-21 CN disclosed
CN-103224474-B The synthesis of tetracycline and the like 哈佛大学校长及研究员协会 2016-08-03 CN disclosed
CN-105814112-A Aliphatic polycarbonate-based surface active agents 萨索尔化学品(美国)有限公司 2016-07-27 CN disclosed
CN-102209532-B Method for reducing small, dense LDL particles METABOLEX INC 2015-07-22 CN disclosed
CN-102365025-A Conjugate-based systems for controlled drug delivery SMARTCELLS INC 2012-02-29 CN disclosed
CN-102014897-A Compounds, compositions and methods for making the same SIGNUM BIOSCIENCES INC 2011-04-13 CN disclosed
CN-1373660-A Method for treating chronic pain using MEK inhibitors WARNER LAMBERT CO (US) 2002-10-09 CN disclosed
CN-1348373-A Use of 17-ketosteroids for the treatment of malaria and Trypanosomiasis HOLLIS EDEN PHARMACEUTICALS (US) 2002-05-08 CN disclosed
CN-1238762-A Piperidine compounds GILEAD SCIENCES INC (US) 1999-12-15 CN disclosed