⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14353832 | 1.00 | — | — | |
| SCHEMBL417484 | 1.00 | — | — | |
| SCHEMBL13262178 | 1.00 | — | — | |
| SCHEMBL417983 | 1.00 | — | — | |
| SCHEMBL2355666 | 1.00 | — | — | |
| SCHEMBL2237318 | 1.00 | — | — | |
| SCHEMBL28310590 | 1.00 | — | — | |
| SCHEMBL2160534 | 1.00 | — | — | |
| SCHEMBL908618 | 0.85 | ACE (0.39) | — | |
| SCHEMBL404285 | 0.84 | ANPEP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945382-B | Substituted piperidines that increase p53 activity and uses thereof | 默沙东公司 | 2020-02-07 | — | — | CN | disclosed |
| EP-2547645-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | JANSSEN PHARMACEUTICALS INC (US) | 2018-07-04 | — | — | EP | disclosed |