SCHEMBL908618

SCHEMBL908618

O=C(O)C1CCC2CC(O)CCC2C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.39
AKR1C3 P42330 1/20 0.38
AKR1C1 Q04828 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GABRR1 P24046 1/20 0.37
PLG P00747 1/20 0.35
PLAT P00750 1/20 0.35
LMNA P02545 1/20 0.35
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
TSHR P16473 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127054 0.88 ACE (0.46) ACEAKR1C3AKR1C1MEN1KMT2A
SCHEMBL7859167 0.88 ACE (0.46) ACEAKR1C3AKR1C1MEN1KMT2A
SCHEMBL8150515 0.88 ACE (0.46) ACEAKR1C3AKR1C1MEN1KMT2A
SCHEMBL14353832 0.85
SCHEMBL417484 0.85
SCHEMBL2355666 0.85
SCHEMBL20344391 0.85
SCHEMBL2237318 0.85
SCHEMBL417983 0.85
SCHEMBL2160534 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060106102-A1 Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) Morand, Eric 2006-05-18 US claimed
US-5621041-A Compatible liquid crystal polymer/polyolefin blends CENTER FOR INNOVATIVE TECHNOLOGY (US) 1997-04-15 US claimed
CN-110753737-B Composition for synthesizing liquid crystal polymer, liquid crystal polymer obtained using the same, and product comprising liquid crystal polymer SK化学株式会社 2024-03-01 CN disclosed
US-10703917-B2 Coating compositions suitable for use with an overcoated photoresist ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-07-07 US disclosed
EP-3636727-A1 COMPOSITION FOR SYNTHESIZING LIQUID CRYSTAL POLYMER, LIQUID CRYSTAL POLYMER FOR ELECTRIC AND ELECTRONIC PRODUCTS USING SAME, POLYMER RESIN COMPOSITION USING SAME, AND MOLDED PRODUCT USING SAME SK Chemicals Co., Ltd. (KR) 2020-04-15 EP disclosed
CN-110753737-A Composition for synthesizing liquid crystal polymer, liquid crystal polymer for electric and electronic products using the same, polymer resin composition using the same, and molded product using the same SK化学株式会社 2020-02-04 CN disclosed
US-20170313889-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-11-02 US disclosed
US-9708493-B2 Coating compositions suitable for use with an overcoated photoresist ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-07-18 US disclosed
US-20160009924-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-14 US disclosed
US-8883407-B2 Coating compositions suitable for use with an overcoated photoresist ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-11-11 US disclosed
US-20110003250-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-01-06 US disclosed
EP-2261738-A2 Coating compositions suitable for use with an overcoated photoresist Rohm and Haas Electronic Materials, L.L.C. (US) 2010-12-15 EP disclosed
EP-1549598-A4 NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) CORTICAL PTY LTD (AU) 2008-01-23 EP disclosed
US-20060106102-A1 Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) Morand, Eric 2006-05-18 US disclosed
EP-1549598-A1 NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) Cortical Pty Ltd (AU) 2005-07-06 EP disclosed
WO-2003104178-A1 NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) CORTICAL PTY LTD (AU) 2003-12-18 WO disclosed
EP-0344099-B1 A polyester and an article made of the same SEIKISUI CHEMICAL CO LTD (JP) 1995-04-12 EP disclosed
US-5235024-A Thermoplastic elastomers, engineering thermoplastics, liquid crystalline polymers SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-08-10 US disclosed
US-5191057-A Engineering plastics and liquid crystal resins for injection molding SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-03-02 US disclosed
EP-0344099-A2 A polyester and an article made of the same SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003250-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST DHPS, HAAO, FTO ACE 3473/4885AKR1C3 202/4885AKR1C1 212/4885
US-10703917-B2 Coating compositions suitable for use with an overcoated photoresist DHPS, HAAO, FTO ACE 3473/4885AKR1C3 202/4885AKR1C1 212/4885
US-20170313889-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST DHPS, HAAO, FTO ACE 3473/4885AKR1C3 202/4885AKR1C1 212/4885
US-20160009924-A1 COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST DHPS, HAAO, FTO ACE 3473/4885AKR1C3 202/4885AKR1C1 212/4885
US-20060106102-A1 Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) MIF, ARG1, MSR1 ACE 1896/4885AKR1C3 1224/4885AKR1C1 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.