Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15877409 | 0.86 | DAO (0.74) | DAOMAPTNPSR1PLA2G10PLA2G2A | |
| SCHEMBL23189011 | 0.83 | MAPT (0.79) | DAOMAPTNPSR1PLA2G10PLA2G2A | |
| SCHEMBL30760383 | 0.83 | DAO (0.56) | DAOMAPTNPSR1PLA2G10PLA2G2A | |
| SCHEMBL30760252 | 0.79 | DAO (0.55) | DAOMAPTNPSR1HPGDMEN1 | |
| SCHEMBL4674028 | 0.76 | DAO (0.49) | DAOMAPTNPSR1PLA2G10PLA2G2A | |
| SCHEMBL9585670 | 0.76 | MAPT (0.50) | DAOMAPTNPSR1HPGDMEN1 | |
| SCHEMBL4674025 | 0.76 | DAO (0.49) | DAOMAPTNPSR1PLA2G10PLA2G2A | |
| Diphenylmethane SCHEMBL18604552 | 0.74 | PLA2G10 (0.71) | MAPTPLA2G10PLA2G2AMEN1KMT2A | |
| Diphenylmethane SCHEMBL8743340 | 0.74 | PLA2G10 (0.71) | MAPTPLA2G10PLA2G2AMEN1KMT2A | |
| Diphenylmethane SCHEMBL28144267 | 0.74 | PLA2G10 (0.71) | MAPTPLA2G10PLA2G2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |