SCHEMBL15877409

SCHEMBL15877409

O=C(O)c1cc(Cc2ccccc2)cs1

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 4/20 0.74
MAPT P10636 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HNF4A P41235 1/20 0.46
CALM1 P0DP23 1/20 0.44
LTB4R Q15722 1/20 0.44
PTPN1 P18031 3/20 0.44
PTPN2 P17706 1/20 0.44
PTPN6 P29350 1/20 0.44
PLA2G10 O15496 1/20 0.43
PLA2G2A P14555 1/20 0.43
LMNA P02545 1/20 0.43
ALAD P13716 2/20 0.42
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
ACMSD Q8TDX5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14488334 0.87 DAO (0.62) DAOMAPTNPSR1ALADPOLB
SCHEMBL23189011 0.86 MAPT (0.79) DAOMAPTNPSR1HNF4ACALM1
SCHEMBL30760383 0.86 DAO (0.56) DAOMAPTNPSR1HNF4ACALM1
SCHEMBL20344489 0.86 DAO (0.56) DAOMAPTNPSR1HNF4ACALM1
SCHEMBL4398550 0.85 DAO (1.00) DAOMAPTNPSR1LTB4RALAD
SCHEMBL30760252 0.85 DAO (0.55) DAOMAPTNPSR1LMNAPOLB
SCHEMBL4674028 0.79 DAO (0.49) DAOMAPTNPSR1HNF4ACALM1
SCHEMBL4674025 0.79 DAO (0.49) DAOMAPTNPSR1HNF4ACALM1
SCHEMBL9585670 0.79 MAPT (0.50) DAOMAPTNPSR1LTB4RLMNA
SCHEMBL1401507 0.76 DAO (0.61) DAOMAPTNPSR1LMNAALAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023246876-A1 MEDICAL USE OF FORMAMIDE DERIVATIVES, FORMAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 上海科技大学 2023-12-28 WO disclosed
CN-117285520-A Medical use of carboxamide derivative, carboxamide derivative and pharmaceutical composition containing carboxamide derivative 上海科技大学 2023-12-26 CN disclosed
US-10188910-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-20180126226-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-05-10 US disclosed
US-20180056137-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-03-01 US disclosed
US-9533195-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2017-01-03 US disclosed
US-20160144241-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2016-05-26 US disclosed
US-9283439-B2 Golf ball DUNLOP SPORTS CO., LTD. (JP) 2016-03-15 US disclosed
US-20140206476-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2014-07-24 US disclosed