Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.88 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335196 | 0.94 | IL6 (1.00) | IL6PLA2G7HTR2CMDM2ALDH1A1 | |
| SCHEMBL18573526 | 0.94 | IL6 (1.00) | IL6PLA2G7HTR2CMDM2ALDH1A1 | |
| SCHEMBL18573562 | 0.94 | IL6 (1.00) | IL6PLA2G7HTR2CMDM2ALDH1A1 | |
| SCHEMBL4581163 | 0.92 | IL6 (0.82) | IL6PLA2G7HTR2CMDM2ALDH1A1 | |
| SCHEMBL20344710 | 0.92 | IL6 (0.82) | IL6PLA2G7 | |
| SCHEMBL18573466 | 0.92 | IL6 (0.90) | IL6ALDH1A1MAPK1 | |
| SCHEMBL20335223 | 0.92 | IL6 (1.00) | IL6ALDH1A1MAPK1 | |
| SCHEMBL18573599 | 0.92 | IL6 (1.00) | IL6ALDH1A1MAPK1 | |
| SCHEMBL18573549 | 0.92 | IL6 (1.00) | IL6ALDH1A1MAPK1 | |
| SCHEMBL20344621 | 0.91 | IL6 (0.83) | IL6PLA2G7HTR2CMDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342768-A1 | [4-(1, 3, 3-TRIMETHYL-2-OXO-3, 4-DIHYDRO-1H-QUINOXALIN-7-YL) PHENOXY]ETHYLOXY COMPOUND OR SALT THEREOF | Santen Pharmaceutical Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |