Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.80 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 8/20 | 0.33 |
| ▸ | DRD4 | P21917 | 7/20 | 0.33 |
| ▸ | DRD3 | P35462 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573561 | 0.96 | IL6 (0.81) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL20344741 | 0.94 | IL6 (0.81) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL20344632 | 0.92 | IL6 (0.81) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL20335202 | 0.92 | IL6 (0.77) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL4581163 | 0.91 | IL6 (0.82) | IL6PLA2G7HTR2CAKR1A1AKR1B1 | |
| SCHEMBL20344707 | 0.91 | IL6 (0.80) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL20344621 | 0.91 | IL6 (0.83) | IL6PLA2G7HTR2C | |
| SCHEMBL4134613 | 0.90 | IL6 (0.84) | IL6PLA2G7HTR2C | |
| SCHEMBL20335214 | 0.90 | IL6 (0.73) | IL6PLA2G7DRD2DRD4DRD3 | |
| SCHEMBL1918700 | 0.90 | IL6 (0.80) | IL6PLA2G7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342768-A1 | [4-(1, 3, 3-TRIMETHYL-2-OXO-3, 4-DIHYDRO-1H-QUINOXALIN-7-YL) PHENOXY]ETHYLOXY COMPOUND OR SALT THEREOF | Santen Pharmaceutical Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |