Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675563 | 0.98 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL2640223 | 0.84 | TSHR (0.70) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011734 | 0.82 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011595 | 0.82 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011646 | 0.82 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011624 | 0.82 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011715 | 0.82 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL18841197 | 0.81 | L3MBTL1 (0.51) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL21184508 | 0.80 | TSHR (0.64) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL25195898 | 0.80 | TSHR (0.64) | L3MBTL1TDP1TSHRHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342768-A1 | [4-(1, 3, 3-TRIMETHYL-2-OXO-3, 4-DIHYDRO-1H-QUINOXALIN-7-YL) PHENOXY]ETHYLOXY COMPOUND OR SALT THEREOF | Santen Pharmaceutical Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |