SCHEMBL20344767

SCHEMBL20344767

CCCN1C(=O)CCc2cc(NS(=O)(=O)Cc3ccc(C(F)(F)F)c(F)c3)ccc21

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.37
TRIM24 O15164 4/20 0.37
CREBBP Q92793 1/20 0.37
HDAC6 Q9UBN7 2/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
KIF11 P52732 2/20 0.36
CES2 O00748 1/20 0.36
PGR P06401 1/20 0.36
P2RX7 Q99572 1/20 0.35
ATAD2 Q6PL18 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KCNT1 Q5JUK3 1/20 0.35
KCNT2 Q6UVM3 1/20 0.35
CHRM1 P11229 1/20 0.34
ALOX5 P09917 1/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344751 0.88 BRD4 (0.41) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL20344747 0.85 BRD4 (0.42) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL15298954 0.82 BRD4 (0.44) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL20344782 0.82 HDAC6 (0.35) TRIM24HDAC6HDAC1HDAC8CES2
SCHEMBL17502924 0.81 HDAC1 (0.44) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL20344768 0.81 BRD4 (0.39) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL20344770 0.80 BRD4 (0.41) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL17771428 0.80 CHRM1 (0.44) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL19148960 0.79 HDAC1 (0.47) BRD4TRIM24CREBBPHDAC6HDAC1
SCHEMBL17502910 0.79 TRIM24 (0.52) BRD4TRIM24CREBBPHDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-11-24 US disclosed
EP-3342766-A1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CYP4F11, RICTOR, MYB BRD4 1887/4885TRIM24 4017/4885CREBBP 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.