Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344734 | 0.89 | ATAD2 (0.38) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL20344768 | 0.83 | BRD4 (0.39) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL20344812 | 0.81 | ATAD2 (0.35) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL18571318 | 0.78 | HDAC1 (0.43) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL20344815 | 0.77 | HDAC1 (0.41) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL24519735 | 0.74 | BRD4 (0.31) | — | |
| SCHEMBL29424983 | 0.71 | BRD4 (0.42) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL20344739 | 0.71 | BRD4 (0.42) | ATAD2HDAC6HDAC1HDAC8CHRM1 | |
| SCHEMBL20344796 | 0.71 | — | — | |
| SCHEMBL22756470 | 0.71 | HDAC1 (0.36) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |