Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344759 | 0.77 | BRAF (0.31) | BRPF1BRAFHPGDBRD4 | |
| SCHEMBL20344802 | 0.70 | HDAC8 (0.34) | HDAC8BRPF1HDAC1HDAC6ATM | |
| SCHEMBL20344751 | 0.68 | BRD4 (0.41) | HDAC8BRPF1HDAC1HDAC6MAPT | |
| SCHEMBL20344770 | 0.68 | BRD4 (0.41) | HDAC8BRPF1HDAC1HDAC6POLB | |
| SCHEMBL24519716 | 0.68 | MEN1 (0.32) | HDAC1HDAC6MAPTPOLBLMNA | |
| SCHEMBL20616467 | 0.65 | BRD4 (0.39) | HDAC8BRPF1HDAC1HDAC6LMNA | |
| SCHEMBL20616466 | 0.65 | BRD4 (0.36) | HDAC8BRPF1HDAC1HDAC6MAPT | |
| SCHEMBL15298954 | 0.65 | BRD4 (0.44) | HDAC8BRPF1HDAC1HDAC6MAPT | |
| SCHEMBL20616472 | 0.65 | PKM (0.37) | HDAC8BRPF1HDAC1HDAC6POLB | |
| SCHEMBL20616456 | 0.64 | BRD4 (0.40) | HDAC8BRPF1HDAC1HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |