Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898103 | 0.83 | BRD4 (0.41) | PARP1BRD4TP53CREBBPBRPF1 | |
| SCHEMBL10358533 | 0.83 | BRD4 (0.41) | PARP1BRD4TP53CREBBPBRPF1 | |
| SCHEMBL4968610 | 0.81 | BRD4 (0.47) | PARP1BRD4TP53CREBBPBRPF1 | |
| SCHEMBL4972202 | 0.80 | CA2 (0.50) | PARP1BRD4TRPV1SMN1; SMN2CREBBP | |
| SCHEMBL5672928 | 0.79 | CREBBP (0.60) | PARP1BRD4TRPV1CREBBPBRPF1 | |
| SCHEMBL31402329 | 0.79 | CREBBP (0.60) | PARP1BRD4TRPV1CREBBPBRPF1 | |
| SCHEMBL3635930 | 0.78 | PARP1 (0.56) | PARP1BRD4TRPV1TP53TSHR | |
| SCHEMBL18128151 | 0.78 | PARP1 (0.56) | PARP1BRD4TRPV1CREBBPBRPF1 | |
| SCHEMBL20983200 | 0.78 | PARP1 (0.56) | PARP1BRD4TRPV1CREBBPBRPF1 | |
| SCHEMBL12540763 | 0.78 | PARP1 (0.56) | PARP1BRD4TRPV1CREBBPBRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598511-B1 | NOVEL STABLE AND HIGHLY TUNABLE METATHESIS CATALYSTS | ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) | 2018-07-04 | — | — | EP | disclosed |