SCHEMBL203456

SCHEMBL203456

Cl[SiH](Cl)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293210 0.97 TSHR (0.37)
SCHEMBL9064098 0.84 TSHR (0.36)
Diphenylamine SCHEMBL8410026 0.84 HSD17B10 (0.60)
SCHEMBL2685390 0.81
SCHEMBL297217 0.79 TSHR (0.39)
SCHEMBL11296187 0.78 ESR1 (0.34)
Water SCHEMBL9174447 0.76 TSHR (0.37)
SCHEMBL22830125 0.76 TSHR (0.37)
SCHEMBL6749463 0.76 ALDH1A1 (0.50)
SCHEMBL21527935 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2018 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117683065-B Phosphine ligand containing silicon-hydrogen group, preparation method and application thereof 华东师范大学 2026-05-19 CN claimed
US-12612422-B2 Method for making a siloxane-(meth)acrylate macromonomer DOW SILICONES CORPORATION (US) 2026-04-28 US claimed
US-20250361603-A1 FIBROUS SILICON-CARBON COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR Shida Shinghwa Advanced Material Group Co., Ltd. (CN) 2025-11-27 US claimed
CN-120157944-A Modified methyl silicone resin and preparation method thereof 山东东湖新材料有限公司 2025-06-17 CN claimed
CN-120058769-A Preparation method for improving conversion rate of aromatic chlorosilane prepared by reduction of aromatic chlorosilane 江苏南大光电材料股份有限公司 2025-05-30 CN claimed
CN-119979085-A Graphene conductive adhesive and preparation method thereof 深圳稀导技术有限公司 2025-05-13 CN claimed
CN-119951586-A ZnCo-ZIF/CeO2Method for catalytic synthesis of phenylchlorosilane and catalyst used in method 浙江大学 2025-05-09 CN claimed
CN-119612491-A Silicon-carbon composite material and preparation method thereof 广东宏璟新能源科技有限公司 2025-03-14 CN claimed
CN-119504838-A Chlorine removal method for chlorosilane hydrolysate 江西蓝星星火有机硅有限公司 2025-02-25 CN claimed
CN-119488901-A Dialkyl maleate hydrogenation catalyst and preparation method thereof 中国石油化工股份有限公司 2025-02-21 CN claimed
US-5136071-A Reduces induction time DOW CORNING CORPORATION (US) 1992-08-04 US claimed
US-5110974-A Thermal disproportionation of arylhalosilanes DOW CORNING CORPORATION (US) 1992-05-05 US claimed
EP-0477765-A2 Thermoplastic, coupled barrier composites THE B.F. GOODRICH COMPANY (US) 1992-04-01 EP claimed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US claimed
US-4746752-A QUATERNARY OR TERTIARY AMINE CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-24 US claimed
US-4678768-A POLYMERS OF HIGH STEREOREGULARITY AND BULK DENSITY TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1987-07-07 US claimed
US-4567286-A Preparation of hydrogenated silanes by redistribution of hydrosilanes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-01-28 US claimed
US-4405590-A Dismutation/redistribution of halogenosilanes into silane RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-09-20 US claimed
US-4393229-A HALOGENATION, TRANSALKYLATION GENERAL ELECTRIC COMPANY (US) 1983-07-12 US claimed
US-4089882-A ORGANOHYDROGENSILANE REACTED WITH FLUOROOLEFIN, BINARY CATALYST OF PLATINUM COMPOUND AND STANNOUS CHLORIDE SHIN-ETSU CHEMICAL CO., LTD. (JA) 1978-05-16 US claimed